양극산화와 열수처리한 순수 니오비움 금속의 생체활성 평가
Evaluation of Biocompatibility of Anodized and Hydrothermally Treated Pure Niobium Metal
원대희, 최운재, 이민호, 배태성,
소속 상세정보
원대희 ( Won Dae-Hee ) - 순천대학교 산학협력중심대학 육성사업단
최운재 ( Choi Un-Jae ) - 원광보건대학 치기공과
이민호 ( Lee Min-Ho ) - 전북대학교 치과대학 치과생체재료학교실
배태성 ( Bae Tae-Sung ) - 전북대학교 치과대학 치과재료학교실
KMID : 0362120050270010079
Abstract
This study was performed to investigate the surface properties of electrochemically oxidized pure niobium by anodic oxide and hydrothermal treatment technique. Niobium specimens of 10 10 in dimension were polished sequentially from #600, #800, #1000 emery paper. The surface pure niobium specimens were anodized in an electrolytic solution that was dissolved calcium and phosphate in water. The electrolytic voltage was set in the range of 250 V and the current density
was 10 / . The specimen was hydrothermal treated in high-pressure steam at 300 for 2 hours using an autoclave. Then, specimens were immersed in the Hanks’ solution with pH 7.4 at 37 for 30 days. The surface of specimen was characterized by scanning electron microscope(SEM), energy dispersive X-ray microanalysis(EDX), potentiostat/galvanostat test, and cytotoxicity test. The results obtained was summarized as follows; According to the result of measuring corrosion behavior at 0.9% NaCl, corrosion resistance was improved more specimens treated with anodic oxide than in hydrothermal treated ones. The multi-porous oxide layer on surface treated through anodic oxidation showed a structure that fine pores overlap one another, and the early precipitation of apatite was observed on the surface of hydrothermal treated samples. According to the result of EDX after 30 days deposition in Hanks solution, Ca/P was 1.69 in hydrothermal treated specimens. In MTT test, specimens treated through anodic oxidation and hydrothermal treated ones showed spectrophotometer similar to that of the control group. Thus no significant difference in cytotoxicity was observed (P>0.05).
키워드
Anodizing;Niobium;Hydrothermal treated;Cytotoxicity
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